The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

In the 1960s, Christian Anfinsen postulated that the unique three-dimensional structure of a protein is determined by its amino acid sequence. This work laid the foundation for the sequence-structure-function paradigm, which states that the sequence of a protein determines its structure, and structu...

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Veröffentlicht in:	Biochemical Society transactions Jg. 44; H. 5; S. 1185 - 1200
1. Verfasser:	Babu, M Madan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 15.10.2016
Schlagworte:	Alternative Splicing Amino Acid Sequence Apoptosis - genetics Disease - genetics Humans Intrinsically Disordered Proteins - chemistry Intrinsically Disordered Proteins - genetics Intrinsically Disordered Proteins - metabolism Models, Molecular Protein Conformation Protein Folding Structure-Activity Relationship protein turnover RNA localization alternative splicing gene expression and regulation intrinsically disordered proteins biological networks
ISSN:	1470-8752
Online-Zugang:	Weitere Angaben
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