Non-coding RNA in cancer

Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, i...

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Vydáno v:Essays in biochemistry Ročník 65; číslo 4; s. 625
Hlavní autoři: Yan, Huiwen, Bu, Pengcheng
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 01.10.2021
Témata:
microRNA
cancer
long non-coding RNA
piwi RNA
non-coding RNA
circular RNA
ISSN:1744-1358, 1744-1358
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Shrnutí:Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:1744-1358
1744-1358
DOI:10.1042/EBC20200032