LRRK2 links genetic and sporadic Parkinson's disease

The past two decades in research has revealed the importance of leucine-rich repeat kinase 2 (LRRK2) in both monogenic and sporadic forms of Parkinson's disease (PD). In families, mutations in LRRK2 can cause PD with age-dependent but variable penetrance and genome-wide association studies have...

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Bibliographic Details

Published in:	Biochemical Society transactions Vol. 47; no. 2; p. 651
Main Authors:	Kluss, Jillian H, Mamais, Adamantios, Cookson, Mark R
Format:	Journal Article
Language:	English
Published:	England 30.04.2019
Subjects:	Animals Genome-Wide Association Study - methods Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - genetics Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 - metabolism Mutation - genetics Parkinson Disease - enzymology Parkinson Disease - genetics Protein Serine-Threonine Kinases - genetics leucine-rich repeat kinase genome-wide association studies Parkinson's disease
ISSN:	1470-8752, 1470-8752
Online Access:	Get more information
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