Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior

Adolescence is characterized by drastic behavioral adaptations and comprises a particularly vulnerable period for the emergence of various psychiatric disorders. Growing evidence reveals that the pathophysiology of these disorders might derive from aberrations of normal neurodevelopmental changes in...

Full description

Saved in:

Bibliographic Details
Published in:	The Journal of neuroscience Vol. 35; no. 41; pp. 13975 - 13988
Main Authors:	Schneider, Miriam, Kasanetz, Fernando, Lynch, Diane L, Friemel, Chris M, Lassalle, Olivier, Hurst, Dow P, Steindel, Frauke, Monory, Krisztina, Schäfer, Carola, Miederer, Isabelle, Leweke, F Markus, Schreckenberger, Mathias, Lutz, Beat, Reggio, Patricia H, Manzoni, Olivier J, Spanagel, Rainer
Format:	Journal Article
Language:	English
Published:	United States 14.10.2015
Subjects:	Adolescent Adolescent Behavior - physiology Age Factors Animals Behavior, Animal - drug effects Behavior, Animal - physiology Brain - diagnostic imaging Brain - drug effects Brain - growth & development Cannabinoid Receptor Antagonists - pharmacology Cocaine - administration & dosage Corpus Striatum - cytology Endocannabinoids - metabolism Endocannabinoids - pharmacology Exploratory Behavior - drug effects Exploratory Behavior - physiology Guanosine 5'-O-(3-Thiotriphosphate) - pharmacokinetics Humans In Vitro Techniques Male Maze Learning - drug effects Maze Learning - physiology Models, Animal Mutation - genetics Radionuclide Imaging Rats Rats, Inbred F344 Rats, Transgenic Receptor, Cannabinoid, CB1 - genetics Receptor, Cannabinoid, CB1 - metabolism Risk-Taking Social Behavior Sulfur Isotopes - pharmacokinetics adolescence endocannabinoids reward processing ENU mutagenesis CB1 receptor risk seeking
ISSN:	1529-2401
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!