High‐Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC‐SIGN and Langerin

The “carbohydrate chemical mimicry” exhibited by sp2‐iminosugars has been utilized to develop practical syntheses for analogs of the branched high‐mannose‐type oligosaccharides (HMOs) Man3 and Man5. In these compounds, the terminal nonreducing Man residues have been substituted with 5,6‐oxomethylide...

Full description

Saved in:

Bibliographic Details
Published in:	Chemistry : a European journal Vol. 30; no. 2; pp. e202303041 - n/a
Main Authors:	Herrera‐González, Irene, González‐Cuesta, Manuel, Thépaut, Michel, Laigre, Eugénie, Goyard, David, Rojo, Javier, García Fernández, José M., Fieschi, Franck, Renaudet, Olivier, Nieto, Pedro M., Ortiz Mellet, Carmen
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 08.01.2024 Wiley-VCH Verlag
Subjects:	Binding Sites Carbohydrates Chemical Sciences Chemistry Concanavalin A Concanavalin A - metabolism Conformation Epitopes glycomimetics high-mannose oligosaccharides Humans Lectins Lectins, C-Type - metabolism Mannose Mannose - chemistry Mannose-Binding Lectins - chemistry Mimicry Monosaccharides multivalency NMR Nuclear magnetic resonance Oligosaccharides Oligosaccharides - chemistry Phytochemicals Surface plasmon resonance carbohydrates glycomimetics multivalency lectins high-mannose oligosaccharides
ISSN:	0947-6539, 1521-3765, 1521-3765
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!