A reference ontology for biomedical informatics: the Foundational Model of Anatomy

The Foundational Model of Anatomy (FMA), initially developed as an enhancement of the anatomical content of UMLS, is a domain ontology of the concepts and relationships that pertain to the structural organization of the human body. It encompasses the material objects from the molecular to the macros...

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Veröffentlicht in:Journal of biomedical informatics Jg. 36; H. 6; S. 478 - 500
Hauptverfasser: Rosse, Cornelius, Mejino, José L.V.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Elsevier Inc 01.12.2003
Schlagworte:
Abstracting and Indexing as Topic - methods
Algorithms
Anatomy
Anatomy - classification
Anatomy - standards
Artificial Intelligence
Bioinformatics
Biomedical informatics
Computational Biology - methods
Database Management Systems
Databases, Factual - standards
Developmental biology
Embryology
Humans
Information Storage and Retrieval - methods
Knowledge representation
Linguistics
Mereotopology
Models, Anatomic
National Library of Medicine (U.S.)
Natural Language Processing
Ontology
Semantics
Subject Headings
Terminology as Topic
UMLS
Unified Medical Language System - standards
United States
Vocabulary, Controlled
United States
Embryology
Ontology
Mereotopology
Developmental biology
Biomedical informatics
Knowledge representation
UMLS
Anatomy
Bioinformatics
ISSN:1532-0464, 1532-0480
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:The Foundational Model of Anatomy (FMA), initially developed as an enhancement of the anatomical content of UMLS, is a domain ontology of the concepts and relationships that pertain to the structural organization of the human body. It encompasses the material objects from the molecular to the macroscopic levels that constitute the body and associates with them non-material entities (spaces, surfaces, lines, and points) required for describing structural relationships. The disciplined modeling approach employed for the development of the FMA relies on a set of declared principles, high level schemes, Aristotelian definitions and a frame-based authoring environment. We propose the FMA as a reference ontology in biomedical informatics for correlating different views of anatomy, aligning existing and emerging ontologies in bioinformatics ontologies and providing a structure-based template for representing biological functions.
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ISSN:1532-0464
1532-0480
DOI:10.1016/j.jbi.2003.11.007