Epigenetic rejuvenation by partial reprogramming

Rejuvenation of cells by reprogramming toward the pluripotent state raises increasing attention. In fact, generation of induced pluripotent stem cells (iPSCs) completely reverses age‐associated molecular features, including elongation of telomeres, resetting of epigenetic clocks and age‐associated t...

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Vydané v:	BioEssays Ročník 45; číslo 4; s. e2200208 - n/a
Hlavní autori:	Puri, Deepika, Wagner, Wolfgang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Wiley Subscription Services, Inc 01.04.2023
Predmet:	ageing clock Aging Cell Differentiation Cell fate cell senescence Cellular Reprogramming - genetics Clocks DNA methylation Elongation Epigenesis, Genetic epigenetic Epigenetics Induced Pluripotent Stem Cells interrupted reprogramming iPSC partial reprogramming Pluripotency pluripotent Rejuvenation reprogramming risk Senescence Stem cells Telomeres Teratoma Transcriptomics transient reprogramming pluripotent reprogramming ageing clock transient reprogramming epigenetic iPSC DNA methylation interrupted reprogramming rejuvenation partial reprogramming
ISSN:	0265-9247, 1521-1878, 1521-1878
On-line prístup:	Získať plný text
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