Epigenetic rejuvenation by partial reprogramming

Rejuvenation of cells by reprogramming toward the pluripotent state raises increasing attention. In fact, generation of induced pluripotent stem cells (iPSCs) completely reverses age‐associated molecular features, including elongation of telomeres, resetting of epigenetic clocks and age‐associated t...

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Bibliographic Details
Published in:	BioEssays Vol. 45; no. 4; pp. e2200208 - n/a
Main Authors:	Puri, Deepika, Wagner, Wolfgang
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.04.2023
Subjects:	ageing clock Aging Cell Differentiation Cell fate cell senescence Cellular Reprogramming - genetics Clocks DNA methylation Elongation Epigenesis, Genetic epigenetic Epigenetics Induced Pluripotent Stem Cells interrupted reprogramming iPSC partial reprogramming Pluripotency pluripotent Rejuvenation reprogramming risk Senescence Stem cells Telomeres Teratoma Transcriptomics transient reprogramming pluripotent reprogramming ageing clock transient reprogramming epigenetic iPSC DNA methylation interrupted reprogramming rejuvenation partial reprogramming
ISSN:	0265-9247, 1521-1878, 1521-1878
Online Access:	Get full text
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