Methodological Challenges in Protein Microarray and Immunohistochemistry for the Discovery of Novel Autoantibodies in Paediatric Acute Disseminated Encephalomyelitis

Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune-mediated demyelinating disease affecting mainly children and young adults. Differentiation to multiple sclerosis is not always possible, due to overlapping clinical symptoms and recurrent and multiphasic forms. Until now, immunoglobuli...

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Vydáno v:	International journal of molecular sciences Ročník 18; číslo 3; s. 679
Hlavní autoři:	Peschl, Patrick, Ramberger, Melanie, Höftberger, Romana, Jöhrer, Karin, Baumann, Matthias, Rostásy, Kevin, Reindl, Markus
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 22.03.2017 MDPI
Témata:	Animals Antigens Autoantibodies - immunology Autoantigens - immunology Biomarkers Brain research Child Cluster Analysis Cross Reactions - immunology Disease Encephalomyelitis, Acute Disseminated - diagnosis Encephalomyelitis, Acute Disseminated - immunology Female Glycoproteins Humans Immunoglobulins Immunohistochemistry Male Medical research Membrane Proteins - immunology Multiple sclerosis Myelin-Oligodendrocyte Glycoprotein - immunology Nerve Tissue Proteins - immunology Neurology Patients Peptides Potassium Protein Array Analysis Proteins Proteins - immunology Proteome Proteomics - methods Rats Studies Austria acute disseminated encephalomyelitis autoantibody immunohistochemistry autoantigen protein microarray paediatric
ISSN:	1422-0067, 1661-6596, 1422-0067
On-line přístup:	Získat plný text
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