Statin Use Reduces Decline in Lung Function: VA Normative Aging Study

Decreased lung function has been linked to increased inflammation and oxidative stress. Statins have demonstrated antiinflammatory and antioxidant properties. We investigated the effect of statin use on decline in lung function in the elderly, and whether smoking modified this effect. Our study popu...

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Bibliographic Details
Published in:	American journal of respiratory and critical care medicine Vol. 176; no. 8; pp. 742 - 747
Main Authors:	Alexeeff, Stacey E, Litonjua, Augusto A, Sparrow, David, Vokonas, Pantel S, Schwartz, Joel
Format:	Journal Article
Language:	English
Published:	New York, NY Am Thoracic Soc 15.10.2007 American Lung Association American Thoracic Society
Subjects:	Adult Aged Aged, 80 and over Aging Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Asthma B. Chronic Obstructive Pulmonary Disease Biological and medical sciences Bronchitis Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease, asthma Emergency and intensive respiratory care Forced Expiratory Volume - drug effects Forced Expiratory Volume - physiology Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Inflammation Intensive care medicine Longitudinal Studies Male Medical sciences Medical screening Middle Aged Mortality Oxidative stress Pneumology Questionnaires Smoking Smoking - epidemiology Smoking - physiopathology Statins Vital Capacity - drug effects Vital Capacity - physiology Intensive care Senescence FVC Lung function statins Tobacco smoking smoking Statin derivative FEV1 Resuscitation Antilipemic agent
ISSN:	1073-449X, 1535-4970
Online Access:	Get full text
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