Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies

Polymorphisms in certain inflammatory-related genes have been identified as putative differential risk factors of neurodegenerative diseases with abnormal protein aggregates, such as sporadic Alzheimer’s disease (AD) and sporadic Parkinson’s disease (sPD). Gene expression studies of cytokines and me...

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Vydané v:	International journal of molecular sciences Ročník 17; číslo 2; s. 206
Hlavní autori:	López González, Irene, Garcia-Esparcia, Paula, Llorens, Franc, Ferrer, Isidre
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland MDPI AG 04.02.2016 MDPI
Predmet:	Alzheimer Disease - diagnosis Alzheimer Disease - etiology Alzheimer Disease - metabolism Biomarkers Brain - metabolism Brain - pathology Creutzfeldt-Jakob Syndrome - diagnosis Creutzfeldt-Jakob Syndrome - etiology Creutzfeldt-Jakob Syndrome - genetics Creutzfeldt-Jakob Syndrome - metabolism Cytokines Diagnosis, Differential Disease Progression Gene Expression Regulation Genetic Association Studies Genetic Predisposition to Disease Genotype & phenotype Humans Immune system Inflammation Inflammation - complications Inflammation - genetics Inflammation - metabolism Neurodegeneration Neurodegenerative Diseases - diagnosis Neurodegenerative Diseases - etiology Neurodegenerative Diseases - metabolism Parkinson Disease - diagnosis Parkinson Disease - etiology Parkinson Disease - metabolism Polymorphism Protein Aggregation, Pathological Review Risk Factors RNA, Messenger - genetics Tauopathies - diagnosis Tauopathies - etiology Tauopathies - metabolism Transcriptome Alzheimer’s disease toll-like receptors Creutzfeldt-Jakob’s disease inflammation cytokines tauopathies chemokines complement microglia Parkinson’s disease
ISSN:	1422-0067, 1661-6596, 1422-0067
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