Epstein-Barr virus negativity among individuals older than 60 years is associated with HLA-C and HLA-Bw4 variants and tonsillectomy

Epstein-Barr virus (EBV) infects ≈ 95% of the adult population. The factors that confer protection in the remaining ≈ 5% remain unknown. In an exploratory study, we assessed immunogenetic factors and tonsillectomy in a cohort of 17 EBV-negative and 39 EBV-positive healthy individuals aged >60 yea...

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Bibliographic Details
Published in:	Journal of virology Vol. 87; no. 11; p. 6526
Main Authors:	Durovic, Bojana, Gasser, Olivier, Gubser, Patrick, Sigle, Jörg, Hirsch, Hans H, Stern, Martin, Buser, Andreas, Hess, Christoph
Format:	Journal Article
Language:	English
Published:	United States 01.06.2013
Subjects:	Aged Cohort Studies Disease Resistance Epstein-Barr Virus Infections - genetics Epstein-Barr Virus Infections - immunology Epstein-Barr Virus Infections - virology Female Genotype Herpesvirus 4, Human - genetics Herpesvirus 4, Human - immunology Herpesvirus 4, Human - physiology HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-C Antigens - genetics HLA-C Antigens - immunology Humans Male Middle Aged Tonsillectomy
ISSN:	1098-5514, 1098-5514
Online Access:	Get more information
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