Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells

The development of drugs to treat cancer is hampered by the inefficiency of translating pre-clinical in vitro monoculture and mouse studies into clinical benefit. There is a critical need to improve the accuracy of evaluating pre-clinical drug efficacy through the development of more physiologically...

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Veröffentlicht in:	Lab on a chip Jg. 19; H. 7; S. 1193
Hauptverfasser:	Gioeli, Daniel, Snow, Chelsi J, Simmers, Michael B, Hoang, Stephen A, Figler, Robert A, Allende, J Ashe, Roller, Devin G, Parsons, J Thomas, Wulfkuhle, Julia D, Petricoin, Emanuel F, Bauer, Todd W, Wamhoff, Brian R
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 27.03.2019
Schlagworte:	Biomimetics - methods Carcinoma, Pancreatic Ductal - pathology Cell Proliferation - drug effects Humans Tumor Microenvironment - drug effects
ISSN:	1473-0189, 1473-0189
Online-Zugang:	Weitere Angaben
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