Fabrication of chondroitin sulfate calcium complex and its chondrocyte proliferation in vitro

[Display omitted] •Chondroitin sulfate calcium complex (CSCa) was fabricated by cation exchange method.•Characterization of CSCa was analyzed by EDS, AFM, FTIR, NMR, XRD, TGA and DSC.•Chondrocyte proliferation bioactivity of CSCa was investigated in vitro.•CSCa increased intracellular calcium ions a...

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Bibliographic Details
Published in:	Carbohydrate polymers Vol. 254; p. 117282
Main Authors:	Shen, Qingshan, Zhang, Chunhui, Mo, Haizhen, Zhang, Hongru, Qin, Xiaojie, Li, Juan, Zhang, Zhiqiang, Richel, Aurore
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 15.02.2021
Subjects:	Apoptosis Apoptosis - drug effects bioactive properties Bone care Calcium Calcium - chemistry Calcium - metabolism Calcium - pharmacology calcium receptors Calcium sensing receptors Carboxyl groups CASR protein, human Cell Cycle Cell Cycle - drug effects Cell Proliferation Cell Proliferation - drug effects Cells, Cultured Chemistry Chimie Chondrocyte Chondrocyte proliferation Chondrocytes Chondrocytes - cytology Chondrocytes - drug effects Chondrocytes - metabolism Chondroitin sulfate Chondroitin Sulfates Chondroitin Sulfates - chemical synthesis Chondroitin Sulfates - chemistry Chondroitin Sulfates - pharmacology Food supplements Gene Expression Holding capacity Humans In Vitro Techniques Intracellular calcium Magnetic Resonance Spectroscopy Materials Chemistry Models, Biological Molecular Docking Simulation Molecular Structure nuclear magnetic resonance spectroscopy Organic Chemistry Particle Size Physical, chemical, mathematical & earth Sciences Physique, chimie, mathématiques & sciences de la terre Polymers and Plastics Proliferation Receptors, Calcium-Sensing Receptors, Calcium-Sensing - chemistry Receptors, Calcium-Sensing - genetics Receptors, Calcium-Sensing - metabolism secretion Spectroscopy, Fourier Transform Infrared Structural characteristics sulfates TGFB1 protein, human thermal stability Transforming Growth Factor beta1 Transforming Growth Factor beta1 - metabolism Bone care Chondroitin sulfate Proliferation Calcium Chondrocyte
ISSN:	0144-8617, 1879-1344, 1879-1344
Online Access:	Get full text
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