The role of PD-1/PD-L1 and application of immune-checkpoint inhibitors in human cancers

Programmed cell death protein-1 (PD-1) is a checkpoint receptor expressed on the surface of various immune cells. PD-L1, the natural receptor for PD-1, is mainly expressed in tumor cells. Studies have indicated that PD-1 and PD-L1 are closely associated with the progression of human cancers and are...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 13; p. 964442
Main Authors:	Tang, Qing, Chen, Yun, Li, Xiaojuan, Long, Shunqin, Shi, Yao, Yu, Yaya, Wu, Wanyin, Han, Ling, Wang, Sumei
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 13.09.2022
Subjects:	biomarker clinical application human cancers immunecheckpoint inhibitor Immunology PD-1/PD-L1
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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