Evaluating multiple sclerosis severity loci 30 years after a clinically isolated syndrome

Abstract The first genome-wide significant multiple sclerosis severity locus, rs10191329, has been pathologically linked to cortical lesion load and brain atrophy. However, observational cohorts such as MSBase have not replicated associations with disability outcomes, instead finding other loci. We...

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Vydané v:	Brain communications Ročník 6; číslo 6; s. fcae443
Hlavní autori:	Sahi, Nitin, Haider, Lukas, Chung, Karen, Prados Carrasco, Ferran, Kanber, Baris, Samson, Rebecca, Thompson, Alan J, Trip, S Anand, Brownlee, Wallace, Ciccarelli, Olga, Barkhof, Frederik, Tur, Carmen, Houlden, Henry, Chard, Declan
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	UK Oxford University Press 2024
Predmet:	severity phenotype genetics disease progression multiple sclerosis
ISSN:	2632-1297, 2632-1297
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