Insomnia and hypersomnia in major depressive episode: Prevalence, sociodemographic characteristics and psychiatric comorbidity in a population-based study

To examine (i) the frequency of different sleep complaints (early wake-up, trouble falling asleep, hypersomnia) and their co-occurrence and (ii) the sociodemographic characteristics and psychiatric comorbidity associated with each type of sleep profiles. Data were drawn from the Wave 2 National Epid...

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Veröffentlicht in:Journal of affective disorders Jg. 226; S. 132 - 141
Hauptverfasser: Geoffroy, Pierre A., Hoertel, Nicolas, Etain, Bruno, Bellivier, Frank, Delorme, Richard, Limosin, Frédéric, Peyre, Hugo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Netherlands Elsevier B.V 15.01.2018
Elsevier
Schlagworte:
Adult
Aged
Aged, 80 and over
Bipolar Disorder
Bipolar Disorder - epidemiology
Comorbidity
Depression
Depressive Disorder, Major
Depressive Disorder, Major - epidemiology
Disorders of Excessive Somnolence
Disorders of Excessive Somnolence - epidemiology
Female
Human health and pathology
Humans
Hypersomnia
Insomnia
Life Sciences
Major depressive disorder
Male
Marital Status
Middle Aged
Personality Disorders
Personality Disorders - epidemiology
Prevalence
Psychiatrics and mental health
Sleep disturbance
Sleep Initiation and Maintenance Disorders
Sleep Initiation and Maintenance Disorders - epidemiology
Sleep Wake Disorders
Sleep Wake Disorders - psychology
United States
United States - epidemiology
Young Adult
Sleep disturbance
Depression
Bipolar disorder
Hypersomnia
Insomnia
Major depressive disorder
ISSN:0165-0327, 1573-2517, 1573-2517
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Zusammenfassung:To examine (i) the frequency of different sleep complaints (early wake-up, trouble falling asleep, hypersomnia) and their co-occurrence and (ii) the sociodemographic characteristics and psychiatric comorbidity associated with each type of sleep profiles. Data were drawn from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions, a nationally representative survey of the US adult population (wave 1, 2001–2002; wave 2, 2004–2005). The primary analyses were limited to 3573 participants who had a DSM-IV-TR diagnosis of major depressive episode (MDE) between the two waves. We used a multiple regression model to estimate the strength of independent associations between self-reported sleep complaints, sociodemographic characteristics and lifetime psychiatric comorbidity. Most of participants with MDE (92%) reported significant sleep complaints, from whom 85.2% had insomnia and 47.5% hypersomnia symptoms. The prevalence rates were for insomnia “only” of 48.5%, hypersomnia “only” of 13.7%, and their co-occurrence of 30.2%. We found that several sociodemographic characteristics (gender, age, education, individual and familial income, marital status) and psychiatric disorders (bipolar disorders, post-traumatic disorders and panic disorder) were significantly and independently associated with different sleep profiles. The co-occurrence of insomnia (especially early wake-up) and hypersomnia presented with a two-/three- fold increase risk of bipolar disorders. Definitions of sleep complaints were qualitative and subjective. Sleep complaints are prevalent and heterogeneous in expression during MDE. Sleep disturbance profiles are associated with specific patterns of comorbidity. Our findings highlight the importance of continued research on sleep complaints during MDE while taking into account psychiatric comorbidity. •More than 90% of patients with MDE suffer from sleep complaints.•Insomnia is the complaint the most frequently reported in MDE (~85%),•Hypersomnia is also frequent and is present in ~50% of MDE.•Up to one-third of MDE reported both insomnia and hypersomnia.•Co-occurrence of sleep complaints is associated with BD, PTSD and panic disorder.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0165-0327
1573-2517
1573-2517
DOI:10.1016/j.jad.2017.09.032