Mediterranean diet and non-alcoholic fatty liver disease: new therapeutic option around the corner?

Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in Western countries, being considered as the hepatic manifestation of metabolic syndrome. NAFLD has a common pathogenic background to that of metabolic syndrome, and shares many risk factors such as obesity,...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG Vol. 20; no. 23; p. 7339
Main Authors: Sofi, Francesco, Casini, Alessandro
Format: Journal Article
Language:English
Published: United States 21.06.2014
Subjects:
Diet - adverse effects
Diet, Mediterranean
Humans
Non-alcoholic Fatty Liver Disease - diagnosis
Non-alcoholic Fatty Liver Disease - diet therapy
Non-alcoholic Fatty Liver Disease - epidemiology
Non-alcoholic Fatty Liver Disease - physiopathology
Nutritional Status
Risk Factors
Risk Reduction Behavior
Severity of Illness Index
Treatment Outcome
Weight Loss
Prevention
Diet
Metabolic syndrome
Non-alcoholic fatty liver disease
Mediterranean diet
ISSN:2219-2840, 2219-2840
Online Access:Get more information
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Summary:Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in Western countries, being considered as the hepatic manifestation of metabolic syndrome. NAFLD has a common pathogenic background to that of metabolic syndrome, and shares many risk factors such as obesity, hypertension, insulin resistance and dyslipidemia. Although there is no currently available evidence-based established treatment for NAFLD, all the recommendations from the medical associations indicate that the most effective treatment is to reduce weight through lifestyle modifications. Diet, indeed, plays a key role in the management of NAFLD patients, as both the quantity and quality of the diet have been reported to have a beneficial role in the onset and severity of the liver disease. Among all the diets that have been proposed, a Mediterranean diet was the most effective dietary option for inducing weight loss together with beneficial effects on all the risk factors associated with metabolic syndrome and NAFLD. Over the last few years, research has demonstrated a beneficial effect of a Mediterranean diet in NAFLD. In this review, we will examine all the available data on the association between diet, nutrients and the Mediterranean diet in association with onset and severity of NAFLD.
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ISSN:2219-2840
2219-2840
DOI:10.3748/wjg.v20.i23.7339