Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-I...
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| Vydáno v: | Frontiers in chemistry Ročník 8; s. 496 |
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| Médium: | Journal Article |
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Frontiers Media S.A
17.06.2020
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| ISSN: | 2296-2646, 2296-2646 |
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| Abstract | Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed.Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed. |
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| AbstractList | Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed.Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed. Fluorescence imaging in the second near infrared window (NIR-II, 1,000–1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)—a novel kind of NIR-II nanoprobes—are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed. |
| Author | Cruz, Luis J. Yu, Zhenfeng Eich, Christina |
| AuthorAffiliation | Translational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center , Leiden , Netherlands |
| AuthorAffiliation_xml | – name: Translational Nanobiomaterials and Imaging Group, Department of Radiology, Leiden University Medical Center , Leiden , Netherlands |
| Author_xml | – sequence: 1 givenname: Zhenfeng surname: Yu fullname: Yu, Zhenfeng – sequence: 2 givenname: Christina surname: Eich fullname: Eich, Christina – sequence: 3 givenname: Luis J. surname: Cruz fullname: Cruz, Luis J. |
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| Copyright | Copyright © 2020 Yu, Eich and Cruz. Copyright © 2020 Yu, Eich and Cruz. 2020 Yu, Eich and Cruz |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 Reviewed by: Fan Zhang, Fudan University, China; Hong-Min Meng, Zhengzhou University, China Edited by: Jianhua Zhang, Tianjin University, China This article was submitted to Nanoscience, a section of the journal Frontiers in Chemistry |
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