Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics

Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-I...

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Bibliographic Details
Published in:Frontiers in chemistry Vol. 8; p. 496
Main Authors: Yu, Zhenfeng, Eich, Christina, Cruz, Luis J.
Format: Journal Article
Language:English
Published: Frontiers Media S.A 17.06.2020
Subjects:
cancer theranostics
Chemistry
in vitro and in vivo imaging
modification
NIR-II
rare-earth-doped nanoparticles
ISSN:2296-2646, 2296-2646
Online Access:Get full text
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Summary:Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed.Fluorescence imaging in the second near infrared window (NIR-II, 1,000-1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)-a novel kind of NIR-II nanoprobes-are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed.
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Reviewed by: Fan Zhang, Fudan University, China; Hong-Min Meng, Zhengzhou University, China
Edited by: Jianhua Zhang, Tianjin University, China
This article was submitted to Nanoscience, a section of the journal Frontiers in Chemistry
ISSN:2296-2646
2296-2646
DOI:10.3389/fchem.2020.00496