power swgee: GEE-based power calculations in stepped wedge cluster randomized trials

Stepped wedge cluster randomized trials are increasingly being used to evaluate interventions in medical, public health, educational, and social science contexts. With the longitudinal and crossover nature of a SW-CRT, complex analysis techniques are often needed which makes appropriately powering S...

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Vydáno v:The Stata journal Ročník 22; číslo 4; s. 811
Hlavní autoři: Gallis, John A, Wang, Xueqi, Rathouz, Paul J, Preisser, John S, Li, Fan, Turner, Elizabeth L
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.12.2022
Témata:
statistical power
marginal models
power swgee
group randomized trials
st0001
generalized estimating equations
ISSN:1536-867X
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Popis
Shrnutí:Stepped wedge cluster randomized trials are increasingly being used to evaluate interventions in medical, public health, educational, and social science contexts. With the longitudinal and crossover nature of a SW-CRT, complex analysis techniques are often needed which makes appropriately powering SW-CRTs challenging. In this paper, we introduce a newly-developed SW-CRT power calculator, embedded within the power command in Stata. The power calculator assumes a marginal model (i.e., generalized estimating equations [GEE]) for the primary analysis of SW-CRTs, for which other currently available SW-CRT power calculators may not be suitable. The program accommodates complete cross-sectional and closed-cohort designs, and includes multilevel correlation structures appropriate for such designs. We discuss the methods and formulae underlying our SW-CRT calculator, and provide illustrative examples of the use of power swgee. We provide suggestions about the choice of parameters in power swgee, and conclude by discussing areas of future research which may improve the program.
Bibliografie:ObjectType-Article-1
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ISSN:1536-867X
DOI:10.1177/1536867x221140953