Mathematical programming tools for randomization purposes in small two‐arm clinical trials: A case study with real data

Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods use mathematical programming to construct attractive clinical...

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Vydané v:	Pharmaceutical statistics : the journal of the pharmaceutical industry Ročník 23; číslo 6; s. 794 - 812
Hlavní autori:	Vazquez, Alan R., Wong, Weng‐Kee
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Chichester, UK John Wiley & Sons, Inc 01.11.2024 Wiley Subscription Services, Inc
Predmet:	Adaptive Clinical Trials as Topic Clinical trials covariate‐adaptive trial energy distance Humans Main Paper Mathematical programming minimization method Models, Statistical prior information Random Allocation Randomized Controlled Trials as Topic - methods Randomized Controlled Trials as Topic - statistics & numerical data Research Design - statistics & numerical data Sample Size minimization method energy distance prior information covariate‐adaptive trial
ISSN:	1539-1604, 1539-1612, 1539-1612
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