Variable NK cell receptors exemplified by human KIR3DL1/S1

Variegated expression of variable NK cell receptors for polymorphic MHC class I broadens the range of an individual's NK cell response and the capacity for populations and species to survive disease epidemics and population bottlenecks. On evolutionary time scales, this component of immunity is...

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Veröffentlicht in:	The Journal of immunology (1950) Jg. 187; H. 1; S. 11
Hauptverfasser:	Parham, Peter, Norman, Paul J, Abi-Rached, Laurent, Guethlein, Lisbeth A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.07.2011
Schlagworte:	Alleles Animals Disease Models, Animal Evolution, Molecular Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology Histocompatibility Antigens Class I - metabolism HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-B Antigens - metabolism Humans Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Peptide Fragments - immunology Peptide Fragments - metabolism Phylogeny Receptors, KIR3DL1 - genetics Receptors, KIR3DL1 - immunology Receptors, KIR3DL1 - metabolism Receptors, KIR3DS1 - genetics Receptors, KIR3DS1 - immunology Receptors, KIR3DS1 - metabolism
ISSN:	1550-6606, 1550-6606
Online-Zugang:	Weitere Angaben
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