Down-regulation of SNX1 predicts poor prognosis and contributes to drug resistance in colorectal cancer

As a potential tumor suppressor, the detailed clinical application value of sorting nexin 1 (SNX1) has not been elucidated in colorectal cancer (CRC). The aim of the present study was to evaluate the expression of SNX1 in CRC tissues and to determine its correlation with clinicopathologic characteri...

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Bibliographic Details
Published in:	Tumor biology Vol. 37; no. 5; pp. 6619 - 6625
Main Authors:	Bian, Zehua, Feng, Yuyang, Xue, Yao, Hu, Yaling, Wang, Qifeng, Zhou, Leyuan, Liu, Zhihui, Zhang, Jiwei, Yin, Yuan, Gu, Bing, Huang, Zhaohui
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.05.2016 Springer Nature B.V
Subjects:	Adult Aged Antineoplastic Agents - pharmacology Biomarkers, Tumor Biomedical and Life Sciences Biomedicine Cancer Research Cell Line, Tumor Cell Proliferation Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Down-Regulation Drug resistance Drug Resistance, Neoplasm - genetics Female Fluorouracil - pharmacology Gene Expression Regulation, Neoplastic Humans Kaplan-Meier Estimate Lymphatic Metastasis Male Medical prognosis Middle Aged Neoplasm Grading Neoplasm Staging Original Article Prognosis Sorting Nexins - genetics Studies Tumor Burden Tumors Sorting nexin 1 (SNX1) Prognosis Drug resistance Colorectal cancer (CRC)
ISSN:	1010-4283, 1423-0380
Online Access:	Get full text
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