Protein Microarrays for High Throughput Hydrogen/Deuterium Exchange Monitored by FTIR Imaging

Proteins form the fastest-growing therapeutic class. Due to their intrinsic instability, loss of native structure is common. Structure alteration must be carefully evaluated as structural changes may jeopardize the efficiency and safety of the protein-based drugs. Hydrogen deuterium exchange (HDX) h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences Jg. 25; H. 18; S. 9989
Hauptverfasser:	De Meutter, Joëlle, Goormaghtigh, Erik
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 16.09.2024 MDPI
Schlagworte:	Biological research Biology, Experimental Chemical reactions Conformation Deuterium Exchange Measurement - methods Experiments Fourier transform infrared spectroscopy Fourier transforms Hydrogen - chemistry Ligands Mass spectrometry NMR Nuclear magnetic resonance Protein Array Analysis - methods Proteins Proteins - chemistry Scientific imaging Spectroscopy, Fourier Transform Infrared - methods protein microarrays hydrogen deuterium exchange FTIR spectroscopy
ISSN:	1422-0067, 1661-6596, 1422-0067
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!