LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade

Immune checkpoint blocking antibodies are a cornerstone in cancer treatment; however, they benefit only a subset of patients and biomarkers to guide immune checkpoint blockade (ICB) treatment choices are lacking. We designed this study to identify blood-based correlates of clinical outcome in ICB-tr...

Celý popis

Podrobná bibliografia

Vydané v:	Science translational medicine Ročník 13; číslo 608
Hlavní autori:	Shen, Ronglai, Postow, Michael A, Adamow, Matthew, Arora, Arshi, Hannum, Margaret, Maher, Colleen, Wong, Phillip, Curran, Michael A, Hollmann, Travis J, Jia, Liwei, Al-Ahmadie, Hikmat, Keegan, Niamh, Funt, Samuel A, Iyer, Gopa, Rosenberg, Jonathan E, Bajorin, Dean F, Chapman, Paul B, Shoushtari, Alexander N, Betof, Allison S, Momtaz, Parisa, Merghoub, Taha, Wolchok, Jedd D, Panageas, Katherine S, Callahan, Margaret K
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 25.08.2021
Predmet:	Biomarkers, Tumor Carcinoma, Transitional Cell Humans Immune Checkpoint Inhibitors T-Lymphocytes Urinary Bladder Neoplasms
ISSN:	1946-6242, 1946-6242
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!