ASTM biomechanical study comparing the AxioMed lumbar viscoelastic disc to human lumbar disc data

Artificial disc replacements aim to preserve motion in patients with lumbar disc degeneration, but most do not replicate the natural stiffness of the healthy human lumbar disc. Existing ball-and-socket designs often permit excessive motion and fail to provide the nonlinear, load-dependent stiffness...

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Vydáno v:Clinical biomechanics (Bristol) Ročník 130; s. 106686
Hlavní autoři: Chin, Kingsley R., Chebrolu, Sukanya, Sung, Roger D., Carlson, Jeffrey R., McFarland, Mark W., Spayde, Erik, Costigan, William M., Thompson, Sandra, Lore, Vito, Zimmers, Kari B., Estevez, Hope, Pangarkar, Swapnil, Humad, Aditya, Ilogu, Chukwunonso C., Seale, Jason A.
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.12.2025
Témata:
AxioMed® viscoelastic Total disc replacement
Biomechanical Phenomena
Compressive Strength
Elastic Modulus
Elasticity
Humans
In vitro testing
Intervertebral Disc - physiology
Intervertebral Disc - surgery
Lumbar spine
Lumbar Vertebrae - physiology
Lumbar Vertebrae - surgery
Physical Medicine and Rehabilitation
Prostheses and Implants
Range of Motion, Articular
Spinal biomechanics
Stiffness
Stress, Mechanical
Total disc replacement
Total Disc Replacement - methods
Viscosity
Weight-Bearing
Spinal biomechanics
Total disc replacement
Stiffness
In vitro testing
Lumbar spine
AxioMed® viscoelastic Total disc replacement
ISSN:0268-0033, 1879-1271, 1879-1271
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Shrnutí:Artificial disc replacements aim to preserve motion in patients with lumbar disc degeneration, but most do not replicate the natural stiffness of the healthy human lumbar disc. Existing ball-and-socket designs often permit excessive motion and fail to provide the nonlinear, load-dependent stiffness that characterize native spinal biomechanics. To date, no in vitro study has directly compared the stiffness of a viscoelastic total disc replacement (VTDR) to that of the natural lumbar disc under physiologic conditions. Ten AxioMed® lumbar VTDRs were tested using standardized ASTM protocols in a physiologic environment (PBS at 37 ± 3 °C). Axial compression, flexion-extension, axial rotation and compressive shear stiffness were measured using servohydraulic test systems. An additional five implants underwent static axial loading up to 20,000 N. All values were compared to published stiffness ranges for the healthy human lumbar disc. Axial stiffness ranged from 2.56 to 3.48 kN/mm, overlapping the reported native range of 0.5 to 2.5 kN/mm. Flexion-extension stiffness (1.69–2.14 Nm/deg) matched the physiologic range (0.8–2.5 Nm/deg). Rotation stiffness (0.79–0.83 Nm/deg) was lower than native values (2.0–9.6 Nm/deg), resulting in greater rotational mobility. Compressive shear stiffness (0.49–0.59 kN/mm) fell within the native lumbar disc range (0.4–0.7 kN/mm). All implants withstood static compression to 20,000 N without structural failure. These findings show that the AxioMed® VTDR reproduces lumbar disc stiffness more closely than prior designs. The ability to replicate both compliant and stiff loading zones suggests improved biomechanical performance and segmental stability, supporting its use as a potential alternative to spinal fusion. •Viscoelastic disc replacement mimics native lumbar stiffness across multiple modes.•Axial, flexion-extension and shear stiffness matched published disc values.•Rotation stiffness lower than native, leading to greater segmental mobility.•Static compression sustained 20,000 N without mechanical or functional failure.•First in vitro stiffness study of viscoelastic disc vs. human lumbar disc data.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0268-0033
1879-1271
1879-1271
DOI:10.1016/j.clinbiomech.2025.106686