Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling

We have used the most advanced programs currently available to construct the first three-domain structure of the human thyrotropin receptor (TSHR) using comparative modeling. The model consists of a leucine-rich domain (LRD; amino acids 36-281; porcine ribonuclease inhibitor used as a template for m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Thyroid (New York, N.Y.) Jg. 14; H. 12; S. 991
Hauptverfasser:	Núñez Miguel, Ricardo, Sanders, Jane, Jeffreys, Jennifer, Depraetere, Hilde, Evans, Michele, Richards, Tonya, Blundell, Tom L, Rees Smith, Bernard, Furmaniak, Jadwiga
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2004
Schlagworte:	Animals Antibodies, Monoclonal Epitopes - genetics Humans Hydrogen Bonding Immunoglobulin Fab Fragments - immunology Leucine - physiology Ligands Membranes Mice Mice, Inbred BALB C Models, Biological Models, Molecular Receptors, Thyrotropin - drug effects RNA - genetics RNA - isolation & purification Thyrotropin - pharmacology
ISSN:	1050-7256
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!