Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH

The iPSC Neurodegenerative Disease Initiative (iNDI) is the largest-ever iPSC genome engineering project. iNDI will model more than 100 mutations associated with Alzheimer's disease and related dementias (ADRD) in isogenic iPSC lines. Resulting cell lines and phenotypic datasets will be broadly...

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Vydané v:	Neuron (Cambridge, Mass.) Ročník 109; číslo 7; s. 1080
Hlavní autori:	Ramos, Daniel M, Skarnes, William C, Singleton, Andrew B, Cookson, Mark R, Ward, Michael E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 07.04.2021
Predmet:	Alzheimer Disease - therapy Genetic Engineering - methods Humans Induced Pluripotent Stem Cells - transplantation Neural Stem Cells - transplantation Neurodegenerative Diseases - genetics Neurodegenerative Diseases - therapy Stem Cell Research Stem Cell Transplantation
ISSN:	1097-4199, 1097-4199
On-line prístup:	Zistit podrobnosti o prístupe
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