The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus - potential role in modulation of glucose uptake in neurones?

It is proposed that insulin‐regulated aminopeptidase (IRAP) is the site of action of two peptides, angiotensin IV and LVV‐hemorphin 7, which have facilitatory effects on learning and memory. In fat and muscles, IRAP codistributes with the insulin‐responsive glucose transporter GLUT4 in specialised v...

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Bibliographic Details
Published in:	The European journal of neuroscience Vol. 28; no. 3; pp. 588 - 598
Main Authors:	Fernando, Ruani N., Albiston, Anthony L., Chai, Siew Y.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.08.2008
Subjects:	Angiotensin II - analogs & derivatives Angiotensin II - metabolism Animals Cerebellum - cytology Cerebellum - metabolism Cystinyl Aminopeptidase - metabolism Deoxyglucose - metabolism Glucose - metabolism Glucose Transport Proteins, Facilitative - metabolism glucose transporter Glucose Transporter Type 3 - metabolism Glucose Transporter Type 4 - metabolism Hemoglobins - metabolism Hippocampus - cytology Hippocampus - metabolism Humans Insulin - metabolism Male memory Mice Mice, Inbred C57BL Mice, Knockout Neurons - cytology Neurons - metabolism Peptide Fragments - metabolism
ISSN:	0953-816X, 1460-9568, 1460-9568
Online Access:	Get full text
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