Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants

This randomized trial of RSV F protein nanoparticle vaccination during pregnancy did not show efficacy (according to the prespecified success criterion) against RSV-associated, medically significant lower respiratory tract infection but suggested possible benefits with respect to other RSV-related o...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 383; no. 5; pp. 426 - 439
Main Authors:	Madhi, Shabir A, Polack, Fernando P, Piedra, Pedro A, Munoz, Flor M, Trenholme, Adrian A, Simões, Eric A.F, Swamy, Geeta K, Agrawal, Sapeckshita, Ahmed, Khatija, August, Allison, Baqui, Abdullah H, Calvert, Anna, Chen, Janice, Cho, Iksung, Cotton, Mark F, Cutland, Clare L, Englund, Janet A, Fix, Amy, Gonik, Bernard, Hammitt, Laura, Heath, Paul T, de Jesus, Joanne N, Jones, Christine E, Khalil, Asma, Kimberlin, David W, Libster, Romina, Llapur, Conrado J, Lucero, Marilla, Pérez Marc, Gonzalo, Marshall, Helen S, Masenya, Masebole S, Martinón-Torres, Federico, Meece, Jennifer K, Nolan, Terry M, Osman, Ayman, Perrett, Kirsten P, Plested, Joyce S, Richmond, Peter C, Snape, Matthew D, Shakib, Julie H, Shinde, Vivek, Stoney, Tanya, Thomas, D. Nigel, Tita, Alan T, Varner, Michael W, Vatish, Manu, Vrbicky, Keith, Wen, Judy, Zaman, Khalequ, Zar, Heather J, Glenn, Gregory M, Fries, Louis F
Format:	Journal Article
Language:	English
Published:	Boston Massachusetts Medical Society 30.07.2020
Subjects:	Age Aluminum Antibodies F protein Fusion protein Gestation Hospitalization Hypotheses Hypothesis testing Hypoxemia Infants Infections Nanoparticles Objectives Oxygen saturation Pregnancy Proteins Respiratory diseases Respiratory syncytial virus Respiratory tract diseases Sea level Statistical analysis Vaccination Vaccine efficacy Vaccines Vitamin E Womens health
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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