Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

The human plasma lipidome captures risk for cardiometabolic diseases. To discover new lipid-associated variants and understand the link between lipid species and cardiometabolic disorders, we perform univariate and multivariate genome-wide analyses of 179 lipid species in 7174 Finnish individuals. W...

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Vydané v:	Nature communications Ročník 14; číslo 1; s. 6934 - 15
Hlavní autori:	Ottensmann, Linda, Tabassum, Rubina, Ruotsalainen, Sanni E., Gerl, Mathias J., Klose, Christian, Widén, Elisabeth, Simons, Kai, Ripatti, Samuli, Pirinen, Matti
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 31.10.2023 Nature Publishing Group Nature Portfolio
Predmet:	140/58 45/43 631/114/2163 631/208/205/2138 631/443/319/2723 692/499 Association analysis Blood plasma Cardiovascular disease Cholesterol Coronary artery disease Gene loci Gene mapping Genes Genetic analysis Genomes Health risks Heart diseases High density lipoprotein Humanities and Social Sciences Links Lipids Low density lipoprotein multidisciplinary Multivariate analysis Risk Science Science (multidisciplinary) Species Triglycerides
ISSN:	2041-1723, 2041-1723
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