Decision Tree Algorithm−Based Prediction of Vulnerability to Depressive and Anxiety Symptoms in Caregivers of Children With Glaucoma

Development and validation of a decision tree model (DTM) for prediction of mental health status in Korean caregivers of children with glaucoma. Cross-sectional study. Caregivers of children younger than 18 years with diagnosed primary childhood glaucoma (n = 42), secondary childhood glaucoma (n = 5...

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Bibliographic Details
Published in:American journal of ophthalmology Vol. 239; pp. 90 - 97
Main Authors: Wy, Seoyoung, Choe, Sooyeon, Lee, Yun Jeong, Bak, Eunoo, Jang, Mirinae, Lee, Seung Chan, Ha, Ahnul, Jeoung, Jin Wook, Park, Ki Ho, Kim, Young Kook
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01.07.2022
Elsevier Limited
Subjects:
Activities of daily living
Age
Anxiety
Caregivers
Cataracts
Childhood glaucoma
Children & youth
Congenital diseases
Decision making
Decision trees
Eye surgery
Generalized anxiety disorder
Glaucoma
Medical records
Mental depression
Mental disorders
Mental Health
Patients
Pediatrics
Quality of life
Sociodemographics
Software
Caregivers
Childhood glaucoma
Mental Health
ISSN:0002-9394, 1879-1891, 1879-1891
Online Access:Get full text
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Summary:Development and validation of a decision tree model (DTM) for prediction of mental health status in Korean caregivers of children with glaucoma. Cross-sectional study. Caregivers of children younger than 18 years with diagnosed primary childhood glaucoma (n = 42), secondary childhood glaucoma (n = 51), and glaucoma suspect (GS; n = 36) were prospectively enrolled at Seoul National University Children's Hospital, Seoul, Korea. The participants completed 2 questionnaires, the 9-item Patient Health Questionnaire (PHQ-9) and the 7-item Generalized Anxiety Disorder (GAD-7) Assessment. A DTM analysis for discrimination of those with moderate-to-severe depressive (PHQ-9 score ≥10) and anxiety (GAD-7 score ≥11) symptoms was performed with recursive partitioning algorithms based on the obtained clinical, demographic, and socioeconomic data. The mean PHQ-9 and GAD-7 scores did not significantly differ among the 3 groups (P = .823 for PHQ-9 score; P = .730 for GAD-7 score). The DTM's balanced accuracies were 0.875 (95% CI = 0.778-0.972) for the PHQ-9 score and 0.880 (95% CI = 0.800–0.960) for theGAD-7 score. The DTM of the PHQ-9 revealed that in caregivers of children with glaucoma, depressive symptoms should be strongly suspected when (1) the child has undergone more than 2 glaucoma surgeries; or (2) the visual acuity (VA, converted to logarithm of minimum angle of resolution [logMAR]) in the better eye is worse than 0.4 if the child has had only 1 or no surgery. Evaluation of the number of glaucoma surgeries and VA in the better eye can be a useful decision support tool in predicting mental illness in caregivers of children with glaucoma.
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ISSN:0002-9394
1879-1891
1879-1891
DOI:10.1016/j.ajo.2022.01.025