Retinopathy of prematurity

Retinopathy of prematurity (ROP) is a devastating neurovascular disease of the retina in newborn infants that can lead to vision deficits or even blindness. In this concise review we discuss our current knowledge about diagnosis, etiology, pathogenesis, intervention, and outcomes of the disease. Maj...

Full description

Saved in:

Bibliographic Details
Published in:	Developmental medicine and child neurology Vol. 65; no. 5; pp. 625 - 631
Main Authors:	Dammann, Olaf, Hartnett, M. Elizabeth, Stahl, Andreas
Format:	Journal Article
Language:	English
Published:	England 01.05.2023
Subjects:	Endothelial Growth Factors Humans Infant Infant, Newborn Infant, Premature Retina Retinopathy of Prematurity - diagnosis Retinopathy of Prematurity - etiology Retinopathy of Prematurity - therapy Vascular Endothelial Growth Factor A
ISSN:	0012-1622, 1469-8749, 1469-8749
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Retinopathy of prematurity (ROP) is a devastating neurovascular disease of the retina in newborn infants that can lead to vision deficits or even blindness. In this concise review we discuss our current knowledge about diagnosis, etiology, pathogenesis, intervention, and outcomes of the disease. Major advancements have been made both in categorizing the disease in the new International Classification of Retinopathy of Prematurity, Third Edition classification and in treating severe ROP with anti‐vascular endothelial growth factor (VEGF) agents. New development always creates new questions and opens up new areas of research. We will discuss in this review both the benefits and downsides of the new anti‐VEGF treatment approaches in ROP, especially in light of our improved understanding of the underlying ROP pathophysiology. We also offer pointers to areas where more research is needed. What this paper adds Concise update on all aspects of retinopathy of prematurity (ROP), including advances in understanding and treatment. Benefits and risks of the new treatment method of anti‐vascular endothelial growth factor injections in ROP are discussed. New research areas that deserve attention in the coming years are identified. What this paper adds Concise update on all aspects of retinopathy of prematurity (ROP), including advances in understanding and treatment. Benefits and risks of the new treatment method of anti‐vascular endothelial growth factor injections in ROP are discussed. New research areas that deserve attention in the coming years are identified. This article provides a concise up‐to‐date overview of retinopathy of prematurity and its etiology, pathogenesis, diagnosis, treatment, and outcomes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	0012-1622 1469-8749 1469-8749
DOI:	10.1111/dmcn.15468