Isolation of peptide ligands that interact specifically with human glioma cells

Poor prognosis of high grade gliomas coupled with the difficulty of widespread delivery of therapeutic agents prompted the search into new molecular targets. Our aim is to isolate glioma-specific peptide sequences that can be used for targeted delivery of therapeutic drugs and imaging tracer to accu...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) Jg. 31; H. 4; S. 644 - 650
Hauptverfasser:	Ho, Ivy A.W., Hui, Kam M., Lam, Paula Y.P.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York, NY Elsevier Inc 01.04.2010 Elsevier
Schlagworte:	Amino Acid Sequence Biological and medical sciences Cell Line, Tumor Fundamental and applied biological sciences. Psychology Glioma Glioma - metabolism Glioma - pathology Glioma-specific Humans Ligands Medical sciences Molecular Sequence Data Neoplasm Transplantation Neurology Peptides - genetics Peptides - isolation & purification Peptides - metabolism Phage display Tissue Distribution Transplantation, Heterologous Tumors of the nervous system. Phacomatoses Vector targeting Vertebrates: endocrinology Vector targeting Phage display Glioma-specific Glioma Human Nervous system diseases Targeting Peptides Ligand Cell line Central nervous system disease Tumor Isolation Vector
ISSN:	0196-9781, 1873-5169, 1873-5169
Online-Zugang:	Volltext
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