Clinical concepts for regenerative therapy in intrabony defects
Evidence indicates that periodontal regeneration is an efficacious and predictable procedure for the treatment of isolated and multiple intrabony defects. Meta‐analyses from systematic reviews indicate an added benefit, in terms of clinical attachment level gain, when demineralized freeze‐dried bone...
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| Vydáno v: | Periodontology 2000 Ročník 68; číslo 1; s. 282 - 307 |
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| Hlavní autoři: | , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
Denmark
Blackwell Publishing Ltd
01.06.2015
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| Témata: | |
| ISSN: | 0906-6713, 1600-0757 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | Evidence indicates that periodontal regeneration is an efficacious and predictable procedure for the treatment of isolated and multiple intrabony defects. Meta‐analyses from systematic reviews indicate an added benefit, in terms of clinical attachment level gain, when demineralized freeze‐dried bone allograft, barrier membranes and active biologic products/compounds are applied in addition to open flap debridement. On the other hand, a consistent amount of variability of the outcomes is evident among different studies and within the experimental population of each study. This variability is explained, at least in part, by different patient and defect characteristics. Patient‐related factors include smoking habit, compliance with home oral hygiene and residual inflammation after cause‐related therapy. Defect‐associated factors include defect depth and radiographic angle, the number of residual bony walls, pocket depth and the degree of hypermobility. In addition, surgical‐related variables, such as surgical skill, clinical experience and knowledge, and application of the different regenerative materials, have a significant impact on clinical outcomes. This paper presents a strategy to optimize the clinical outcomes of periodontal regeneration. The surgical design of the flap, the use of different regenerative materials and the application of appropriate passive sutures are discussed in this review along with the scientific foundations. |
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| Bibliografie: | istex:D79E4C7E59F438334B08C167B8BF357995D30610 ArticleID:PRD12048 ark:/67375/WNG-34KMSVRJ-5 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 0906-6713 1600-0757 |
| DOI: | 10.1111/prd.12048 |