Target-mediated self-assembly of DNA networks for sensitive detection and intracellular imaging of APE1 in living cells

Herein, giant DNA networks were assembled from two kinds of functionalized tetrahedral DNA nanostructures (f-TDNs) for sensitive detection and intracellular imaging of apurinic/apyrimidinic endonuclease 1 (APE1) as well as gene therapy in tumor cells. Impressively, the reaction rate of the catalytic...

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Bibliographic Details

Published in:	Chemical science (Cambridge) Vol. 14; no. 9; pp. 2318 - 2324
Main Authors:	Zhou, Xue-Mei, Zhuo, Ying, Yuan, Ruo, Chai, Ya-Qin
Format:	Journal Article
Language:	English
Published:	England Royal Society of Chemistry 01.03.2023 The Royal Society of Chemistry
Subjects:	Apoptosis Cells (biology) Chemistry Deoxyribonucleic acid DNA Gene therapy Medical imaging Nanostructure Networks Reagents Self-assembly Tumors
ISSN:	2041-6520, 2041-6539
Online Access:	Get full text
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