Type 1 diabetes: etiology, immunology, and therapeutic strategies

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We only know for sure that autoimmunity is the predominant effector mechanism of T1D, but may not be its primary cause...

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Vydané v:	Physiological reviews Ročník 91; číslo 1; s. 79
Hlavní autori:	van Belle, Tom L, Coppieters, Ken T, von Herrath, Matthias G
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.01.2011
Predmet:	Animals Clinical Trials as Topic Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - therapy Genetic Predisposition to Disease Humans Prediabetic State - diagnosis Primary Prevention
ISSN:	1522-1210, 1522-1210
On-line prístup:	Zistit podrobnosti o prístupe
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