Principal-Component Analysis-Based Measures of PET Data Closely Reflect Neuropathologic Staging Schemes

Voxel-based principal-component analysis allows for an identification of patterns of glucose metabolism and amyloid deposition related to the conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD). The present study aimed to validate these AD conversion-related patterns (ADCRPs) a...

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Bibliographic Details
Published in:	The Journal of nuclear medicine (1978) Vol. 62; no. 6; p. 855
Main Authors:	Blazhenets, Ganna, Frings, Lars, Sörensen, Arnd, Meyer, Philipp T
Format:	Journal Article
Language:	English
Published:	United States 01.06.2021
Subjects:	Aged Alzheimer Disease - diagnostic imaging Alzheimer Disease - metabolism Alzheimer Disease - pathology Cognitive Dysfunction - diagnostic imaging Cognitive Dysfunction - metabolism Cognitive Dysfunction - pathology Female Fluorodeoxyglucose F18 Humans Image Processing, Computer-Assisted - methods Male Middle Aged Neuroimaging Positron-Emission Tomography Principal Component Analysis 18F-FDG PET conversion pattern Thal phase Braak tangle stage amyloid PET
ISSN:	1535-5667, 1535-5667
Online Access:	Get more information
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