Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2)

The human major histocompatibility complex class I chain-related A gene (MICA) and the MICB gene are newly identified members of the major histocompatibility complex class I chain-related gene family. We demonstrate here that oxidative stress, induced by H 2O 2, promoted MICA (2.2-fold) and MICB (3....

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Bibliographic Details
Published in:	Biochimica et biophysica acta Vol. 1526; no. 1; pp. 10 - 12
Main Authors:	Yamamoto, Kazuo, Fujiyama, Yoshihide, Andoh, Akira, Bamba, Tadao, Okabe, Hidetoshi
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 03.04.2001
Subjects:	Caco-2 Cells - metabolism Gene Expression Regulation H 2O 2 Histocompatibility Antigens Class I - biosynthesis Histocompatibility Antigens Class I - genetics Humans Hydrogen Peroxide Membrane Proteins - metabolism MICA MICB Oxidative Stress Reverse Transcriptase Polymerase Chain Reaction H 2O 2 Oxidative stress MICA MICB
ISSN:	0304-4165, 0006-3002, 1872-8006
Online Access:	Get full text
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