Tumor lymphangiogenesis and melanoma metastasis

Malignant melanomas of the skin primarily metastasize to lymph nodes, and the detection of sentinel lymph node metastases serves as an important prognostic parameter. There is now compelling evidence that melanomas can induce lymphangiogenesis (growth of lymphatic vessels), mainly at the tumor–strom...

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Veröffentlicht in:	Journal of cellular physiology Jg. 216; H. 2; S. 347 - 354
Hauptverfasser:	Rinderknecht, Matthias, Detmar, Michael
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.08.2008
Schlagworte:	Animals Biomarkers, Tumor - metabolism Intercellular Signaling Peptides and Proteins - metabolism Lymph Nodes - pathology Lymphangiogenesis - physiology Lymphatic Metastasis Lymphatic Vessels - metabolism Lymphatic Vessels - pathology Melanoma - diagnosis Melanoma - pathology Prognosis Skin Neoplasms - diagnosis Skin Neoplasms - pathology Vascular Endothelial Growth Factor A - metabolism
ISSN:	0021-9541, 1097-4652, 1097-4652
Online-Zugang:	Volltext
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