Box–Behnken experimental design for extraction optimization of alkaloids from Erythrina verna Vell. trunk barks and LC Method Validation

[Display omitted] •An HPLC-DAD method for alkaloid quantification of E. verna trunk barks was validated.•11-hydroxyerythratidinone was identified as the major compound of E. verna.•The alkaloid extraction of E. verna was optimized by a Box-Behnken design.•The predicted optimal yield was 0.625 g% of...

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Bibliographic Details
Published in:	Industrial crops and products Vol. 133; pp. 250 - 258
Main Authors:	Rambo, Douglas F., Biegelmeyer, Renata, Toson, Natally S.B., Dresch, Roger R., Moreno, Paulo R.H., Henriques, Amélia T.
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01.07.2019
Subjects:	Alkaloids Box-Behnken design Erythrina falcata Erythrina velutina Erythrina verna experimental design flowers gas chromatography-mass spectrometry high performance liquid chromatography HPLC-DAD industry leaves maceration mathematical models Quality control regression analysis tranquilizers Alkaloids Erythrina verna HPLC-DAD Box-Behnken design Quality control
ISSN:	0926-6690, 1872-633X
Online Access:	Get full text
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