Expression of connective tissue growth factor in asthmatic airway smooth muscle cells

There is strong evidence to implicate transforming growth factor-beta in the remodeling that occurs in asthma, as levels are increased in bronchial lavage fluid and gene expression is increased in bronchial tissue. Transforming growth factor-beta is also known to increase the release of collagen fro...

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Veröffentlicht in:	American journal of respiratory and critical care medicine Jg. 167; H. 1; S. 71
Hauptverfasser:	Burgess, Janette K, Johnson, Peter R A, Ge, Qi, Au, Wendy W, Poniris, Maree H, McParland, Brent E, King, Greg, Roth, Michael, Black, Judith L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.01.2003
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Asthma - metabolism Blotting, Western Bronchi - cytology Cells, Cultured Connective Tissue Growth Factor Female Humans Immediate-Early Proteins - analysis Immediate-Early Proteins - genetics Immunohistochemistry Intercellular Signaling Peptides and Proteins - analysis Intercellular Signaling Peptides and Proteins - genetics Male Middle Aged Muscle, Smooth - cytology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Transforming Growth Factor beta - pharmacology Transforming Growth Factor beta1
ISSN:	1073-449X
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