Recent advances in the management of AL Amyloidosis

Summary Immunoglobulin light chain (AL) amyloidosis, the most common of the systemic amyloidosis, is characterized by the deposition of amyloid fibrils that derive from the aggregation of misfolded monoclonal immunoglobulin light chains. Amyloid fibrils disrupt tissue architecture and the pre‐fibril...

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Bibliographic Details
Published in:	British journal of haematology Vol. 172; no. 2; pp. 170 - 186
Main Authors:	Kastritis, Efstathios, Dimopoulos, Meletios A.
Format:	Journal Article
Language:	English
Published:	England 01.01.2016
Subjects:	Amyloidosis - diagnosis Amyloidosis - immunology Amyloidosis - therapy heart failure Humans Immunoglobulin Light Chains - metabolism Immunoglobulin Light-chain Amyloidosis immunoglobulins light chains mass spectrometry Melphalan - therapeutic use monoclonal antibodies Myeloablative Agonists - therapeutic use Plasma Cells - drug effects Plasma Cells - pathology Risk Assessment - methods Stem Cell Transplantation - methods Treatment Outcome heart failure mass spectrometry light chains immunoglobulins monoclonal antibodies
ISSN:	0007-1048, 1365-2141, 1365-2141
Online Access:	Get full text
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