3S: Shotgun secondary structure determination of long non-coding RNAs

Long non-coding RNAs (lncRNAs) have emerged as an important class of RNAs playing key roles in development, disease and epigenetics. Knowledge of lncRNA structure may be critical in understanding function for many lncRNA systems. Due to the enormous number of possible folds for these sequences, seco...

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Bibliographic Details
Published in:	Methods (San Diego, Calif.) Vol. 63; no. 2; pp. 170 - 177
Main Authors:	Novikova, Irina V., Dharap, Ashutosh, Hennelly, Scott P., Sanbonmatsu, Karissa Y.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 15.09.2013
Subjects:	Base Pairing Base Sequence DNA, Complementary epigenetics Humans Inverted Repeat Sequences lncRNA lncRNA structure Long non-coding RNA Long non-coding RNA structure Molecular Sequence Data non-coding RNA nucleotide sequences prediction Reverse Transcriptase Polymerase Chain Reaction RNA, Double-Stranded RNA, Long Noncoding - biosynthesis RNA, Long Noncoding - chemistry RNA, Long Noncoding - genetics Secondary structure Steroid receptor RNA activator lncRNA Steroid receptor RNA activator lncRNA structure Secondary structure Long non-coding RNA structure Long non-coding RNA
ISSN:	1046-2023, 1095-9130, 1095-9130
Online Access:	Get full text
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