Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness

Polynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration. This review aims to provide an overview of the current practices and perceived effectiveness of polynucleotides in...

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Vydáno v:International journal of molecular sciences Ročník 25; číslo 15; s. 8224
Hlavní autoři: Lee, Kar Wai Alvin, Chan, Kwin Wah Lisa, Lee, Angela, Lee, Cheuk Hung, Wan, Jovian, Wong, Sky, Yi, Kyu-Ho
Médium: Journal Article
Jazyk:angličtina
Vydáno: Switzerland MDPI AG 01.08.2024
Témata:
Angiogenesis
Bioavailability
Care and treatment
Cell growth
Cohort analysis
Collagen
Cosmetic Techniques
Deoxyribonucleic acid
DNA
Drug dosages
Esthetics
Evidence-based medicine
Gene expression
Growth factors
Humans
Hyaluronic acid
Hydration
Ingredients
Kinases
Medicine
Nucleic acids
Nucleotides
Polynucleotides - therapeutic use
Ribonucleic acid
RNA
Skin
Skin Aging - drug effects
Transcription factors
South Korea
cosmetic medicine
facial appearance
polynucleotides
aesthetic medicine
wrinkle depth
skin texture
ISSN:1422-0067, 1661-6596, 1422-0067
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Shrnutí:Polynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration. This review aims to provide an overview of the current practices and perceived effectiveness of polynucleotides in aesthetic medicine. A comprehensive search of the literature was conducted using keywords related to polynucleotides, cosmetic application, and aesthetic application. Studies were selected based on their relevance to aesthetic medicine and the inclusion of human subjects. The review found that polynucleotides have been used to improve skin texture, reduce wrinkle depth, and enhance facial appearance. The studies reported varying degrees of efficacy and safety, with some studies demonstrating significant improvements in skin elasticity and hydration. However, others reported limited or no benefits. The review also highlighted the need for further research to establish the optimal use and efficacy of polynucleotides in aesthetic medicine. While the existing literature suggests that polynucleotides may have potential benefits in aesthetic medicine, more research is needed to fully understand their mechanisms of action and optimal use. Clinicians should be aware of the current limitations and potential risks associated with the use of polynucleotides in aesthetic medicine.
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ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms25158224