Factors affecting the postoperative survival rate of obese Asian patients with endometrial cancer

The objective of this study was to explore the factors that influence overall survival in obese patients with endometrial cancer (EC). The retrospective study included patients with EC who were treated between 2000 and April 2013. Subjects were divided into the following groups based on body mass in...

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Vydáno v:Journal of obstetrics and gynaecology Ročník 45; číslo 1; s. 2480856
Hlavní autoři: Gao, Huiqiao, Lu, Qi, Zhang, Jianxin
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Taylor & Francis Group 01.12.2025
Témata:
Adult
Aged
Asian People
Body Mass Index
Endometrial cancer
Endometrial Neoplasms - complications
Endometrial Neoplasms - mortality
Endometrial Neoplasms - surgery
Female
Humans
Kaplan-Meier Estimate
Lymphatic Metastasis
Middle Aged
obesity
Obesity - complications
Obesity - mortality
Overweight - complications
Prognosis
Retrospective Studies
Risk Factors
Survival Rate
Endometrial cancer
survival rate
obesity
ISSN:0144-3615, 1364-6893, 1364-6893
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Shrnutí:The objective of this study was to explore the factors that influence overall survival in obese patients with endometrial cancer (EC). The retrospective study included patients with EC who were treated between 2000 and April 2013. Subjects were divided into the following groups based on body mass index (BMI): non-obese (<24.0 kg/m ), overweight (24.0-28.0 kg/m ) and obese (>28.0 kg/m ). Survival data were estimated using Kaplan-Meier's curves and compared using log-rank statistics. A total of 280 cases were enrolled, including 22.5% in non-obese group, 42.9% in overweight group and 34.6% in obese group. Among different BMI groups, obese EC patients with diabetes have a lower survival rate (  = .041), and obese EC patients with menopause have a lower survival rate (  = .021). The survival rate of overweight EC patients was significantly reduced if vascular thrombus and lymph node metastasis were found during operation (  < .001). Our data suggest that the association of obese EC patients with menstrual status, diabetes and intraoperative vasculature embolus and lymph node metastasis significantly affects postoperative survival. In all subjects, the relevant factors were independent prognostic factors in patients with obese.
Bibliografie:ObjectType-Article-1
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ISSN:0144-3615
1364-6893
1364-6893
DOI:10.1080/01443615.2025.2480856