Ex Vivo production of platelets from stem cells

Summary Stem cell technology holds great promise for transfusion medicine, and generation of platelets from stem cells would be transformative. Platelet transfusions are life saving for millions of people and the clinical demand for platelets continues to increase: there is a real need to increase t...

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Bibliographic Details
Published in:	British journal of haematology Vol. 165; no. 2; pp. 237 - 247
Main Authors:	Avanzi, Mauro P., Mitchell, William Beau
Format:	Journal Article
Language:	English
Published:	England 01.04.2014
Subjects:	Animals Antigens, CD34 - metabolism Blood Platelets - cytology Blood Platelets - metabolism Cell Culture Techniques Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Gene Expression Regulation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism megakaryocyte Megakaryocytes - cytology Megakaryocytes - metabolism megakaryocytopoiesis Platelet stem cells Stem Cells - cytology Stem Cells - metabolism Thrombopoiesis - physiology transfusion medicine megakaryocyte stem cells transfusion medicine Platelet megakaryocytopoiesis
ISSN:	0007-1048, 1365-2141, 1365-2141
Online Access:	Get full text
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