Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America

Iron deficiency is present in approximately 50% of patients with symptomatic heart failure and is independently associated with worse functional capacity, lower quality of, life and increased mortality. The purpose of this document is to summarize current knowledge of how iron deficiency is defined...

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Vydáno v:Journal of cardiac failure Ročník 29; číslo 7; s. 1059 - 1077
Hlavní autoři: Beavers, Craig J., Ambrosy, Andrew P., Butler, Javed, Davidson, Beth T., Gale, Stormi E., PIÑA, Ileana L., Mastoris, Ioannis, Reza, Nosheen, Mentz, Robert J., Lewis, Gregory D.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Elsevier Inc 01.07.2023
Témata:
Anemia, Iron-Deficiency - diagnosis
Anemia, Iron-Deficiency - epidemiology
Heart failure
Heart Failure - complications
Heart Failure - diagnosis
Heart Failure - epidemiology
Humans
Iron
Iron Deficiencies
iron deficiency
Heart failure
iron deficiency
ISSN:1071-9164, 1532-8414, 1532-8414
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Shrnutí:Iron deficiency is present in approximately 50% of patients with symptomatic heart failure and is independently associated with worse functional capacity, lower quality of, life and increased mortality. The purpose of this document is to summarize current knowledge of how iron deficiency is defined in heart failure and its epidemiology and pathophysiology, as well as pharmacological considerations for repletion strategies. This document also summarizes the rapidly expanding array of clinical trial evidence informing when, how, and in whom to consider iron repletion. •Iron deficiency is a common co-morbidity in patients with heart failure.•The use of intravenous iron therapy has demonstrated improvement in quality of life and reduced readmissions.•Further research is needed to determine is needed to determine if this leads to improvement mortality or in all subsets of heart failure, such as preserved ejection fraction.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1071-9164
1532-8414
1532-8414
DOI:10.1016/j.cardfail.2023.03.025