Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America

Iron deficiency is present in approximately 50% of patients with symptomatic heart failure and is independently associated with worse functional capacity, lower quality of, life and increased mortality. The purpose of this document is to summarize current knowledge of how iron deficiency is defined...

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Veröffentlicht in:Journal of cardiac failure Jg. 29; H. 7; S. 1059 - 1077
Hauptverfasser: Beavers, Craig J., Ambrosy, Andrew P., Butler, Javed, Davidson, Beth T., Gale, Stormi E., PIÑA, Ileana L., Mastoris, Ioannis, Reza, Nosheen, Mentz, Robert J., Lewis, Gregory D.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Elsevier Inc 01.07.2023
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ISSN:1071-9164, 1532-8414, 1532-8414
Online-Zugang:Volltext
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Zusammenfassung:Iron deficiency is present in approximately 50% of patients with symptomatic heart failure and is independently associated with worse functional capacity, lower quality of, life and increased mortality. The purpose of this document is to summarize current knowledge of how iron deficiency is defined in heart failure and its epidemiology and pathophysiology, as well as pharmacological considerations for repletion strategies. This document also summarizes the rapidly expanding array of clinical trial evidence informing when, how, and in whom to consider iron repletion. •Iron deficiency is a common co-morbidity in patients with heart failure.•The use of intravenous iron therapy has demonstrated improvement in quality of life and reduced readmissions.•Further research is needed to determine is needed to determine if this leads to improvement mortality or in all subsets of heart failure, such as preserved ejection fraction.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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content type line 23
ISSN:1071-9164
1532-8414
1532-8414
DOI:10.1016/j.cardfail.2023.03.025